Digital pathology and digital histology slide scanners from 3DHistech... both fluorescence and brightfield in one scanner

Microscope slide scanning technology represents a huge change in the workflow of pathology and histology researchers performing brightfield and fluorescence microscopy.

Rather than spending hours peering into a microscope in a cramped position, slide scanning enables researchers to fully examine their virtual microscope slides in minutes from the comfort of their desks.

Collaboration with other research groups and obtaining second opinions becomes simple. With the amount of time saved and ease of analysis, larger studies over more samples are possible. This increases productivity and enhances the quality of the research.

  • Automate tedious tasks
  • Eliminate subjectivity in analysis
  • Increase throughput and quality of results
  • Fully document conclusions

The 3D Histech digital microscopy solution produces an image of any glass slide that is as detailed as if you were looking down the microscope itself.

Simple to use

The live camera feature lets you preview the slide directly, equivalent to looking down the microscope. This lets you check that your sample looks acceptable and focuses well, before you run the scan. The live camera is particularly useful for fluorescence slides. You are able to verify both the sample location and the presence of a fluorescence signal before you scan the slide.

To give fast, automated, unattended operation, the scanner automatically detects the tissue and coverslip. The slide scanner then only scans the areas that contain tissue.

The Pannoramic scanners are compatible with the full range of Semrock fluorescence filters. They hold up to 9 filter cubes at once. Whichever fluorophores you use, automated imaging is possible.

Sharp, detailed images

The slide scanner captures thousands of images with the objective of the microscope at maximum magnification; each focused to gain as sharp and detailed an image as possible. Carl Zeiss Plan-ApoChromat objectives provide the best resolution, flatness and colour correction available to give you clear, detailed, high quality images. A high-speed digital camera acquires the images to create accurate, crisp virtual slides.

The z-stacking feature takes pictures of each image using multiple focus values. You can set the number of focus values and the difference between them. This ability means that you do not miss any details, particularly when scanning thicker samples and FISH slides.

Advanced image processing algorithms seamlessly stitch the images together. The extended focusing algorithm divides the z-stack pictures into small tiles and keeps the sharpest to create a single picture. Unlike some scanners, 3D Histech system virtual slides do not have gaps, lines or any other visible differences where images join.

Although the scanner is fully automated, the software allows you to tweak the capture settings. This enables you to configure the system for the best possible image quality when working with unusual or difficult samples.

Fast, efficient workflow

Each image section capture takes just milliseconds to execute, including repositioning and refocusing. In total, the average slide takes less than 3 minutes to scan. Once one virtual slide is complete, the next microscope slide scan begins within seconds.

The high-speed image compression algorithms save space while maintaining the image quality. The free virtual microscopy viewing software loads higher resolution images as you zoom in, to reveal finer detail. Because this makes loading times insignificant, you can view your virtual slides instantly.

Digital microscope slide navigation is quick and intuitive.

The bar code reader automatically identifies your slides. The scanner then gives an automatic choice of scan settings and save locations. This improves workflow as it helps to eliminate data entry errors and automate the scanning process.

Reliable

Pannoramic scanners do not require regular calibration or maintenance by the end user. The hardware and software process slide after slide with minimal downtime.

For your piece of mind, we offer a range of service packages to ensure that your virtual microscopy scanner continues to give the best performance possible. These include the latest software updates, to continually improve your scanning facility.

3D Histech Pannoramic microscope slide scanners are currently installed in over 400 laboratories worldwide. These range from small clinical institutes to high throughput shared facilities.


3DHistech Slide Scanners
Brightfield & fluorescence slides
Brightfield Fluorescence

Image of squid embryo taken with Pannoramic MIDI.

Pannoramic Model Description
Quotation
Pannoramic DESK The Pannoramic DESK histology slide scanner performs brightfield scanning on a single slide per run.
Qty:
Pannoramic MIDI The MIDI slide scanner has a 12-slide capacity, for reasonable time between loading batches in medium sized labs. This model has both fluorescence and brightfield scanning capability. Fluorescence scanning can be included at the time of purchase or as a later upgrade.
Qty:
Pannoramic SCAN The SCAN has 150 slide capacity for high throughput digital pathology, plus both fluorescence and brightfield scanning capability. Fluorescence scanning can be included at the time of purchase or as a later upgrade.
Qty:
Pannoramic 250 Flash The Pannoramic 250 is a next generation digital pathology slide scanner that has both high speed and high capacity.

This model handles up to 250 slides, with fluorescence and brightfield scanning capability. Fluorescence scanning can be included at the time of purchase or as a later upgrade.
  • Higher speed scanning for faster workflow & higher throughput – 1.5 mins per 15x15mm tissue
  • Darkfield tissue detection – As the scanner can accurately locate the sample, this speeds up & fully automates fluorescence scanning.
  • Motorized camera and objective changers further enhance flexibility and future upgradability
  • LED fluorescent illumination with 20000+ hour lifetime consistently gives the best quality images . The performance remains high and the source is always aligned.
Qty:
Virtual Microscope Viewing and Analysis Software
Slide_Digitisation.pdf
CaseCenter server – organise your virtual slides

Download the latest version of Pannoramic Viewer / Mirax Viewer

Existing Pannoramic / Mirax user? Contact us about a trial of our image analysis and management software.

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